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ASH 2025 Multiple Myeloma Highlights | Bispecifics, CAR‑T, Gene Therapy & Market Signals

Insights Details

Month: Jan 26

Tags: ASH 2025, Conference, Pre-clinical, Phase 1, Phase 2, Phase 3, US FDA, EMA, Company Profile, Product profile, Deal Analysis, Landscape, Global Market Size, Clinical trials, Result Analysis, News Analysis, Social Media, KOL Profile

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About topic:

This video is basically a “big‑picture” debrief of ASH 2025 in multiple myeloma, aimed at people in pharma and biotech rather than front‑line clinicians. It walks through the most important new data on bispecifics, CAR‑T, trispecifics, gene and targeted therapies, and combos like Tec‑Dara, and explains how they could change standard treatment across different disease stages. On top of the science, it also talks about how big and fast‑growing the MM market is, what regulators are doing, how crowded the field is, and what people are saying on social media, to help teams spot opportunities, partnerships, and portfolio moves

ASH 2025 Multiple Myeloma Highlights | Bispecifics, CAR‑T, Gene Therapy & Market Signals

Highlights:

In multiple myeloma, treatment is moving earlier and getting more intensive: drugs like bispecifics, trispecifics, CAR T, and gene/targeted therapies are no longer just last-ditch options, with Tecvayli based “Tec Dara” and a Kite CAR T looking strong enough to change routine care in relapsed disease
MM development is becoming more biomarker‑ and depth‑of‑response‑driven, as MRD negativity gains traction as a key regulatory and clinical endpoint and agents like INMMyCAR gene therapy
Johnson & Johnson is leaning hard into myeloma, building a big toolkit (antibodies, ADCs, bispecifics, trispecifics, and cell therapies) and backing it up with promising early data from its trispecific (BCMA×GPRC5D×CD3, monthly dosing) and Tecvayli based combos
The field is crowded and global, with fast moving Asian/Chinese players and evolving US rules: current guidelines still rely on transplant plus daratumumab/lenalidomide, but new ASH data and incentives like US priority vouchers are nudging systems to make room for more bispecific and CAR T approaches that are effective, manufacturable in the US, and at least somewhat affordable
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